The Researcher Workbench is a cloud-based platform where registered researchers can access Registered and Controlled Tier data. Its powerful tools support data analysis and collaboration. Integrated help and educational resources are provided through the Workbench User Support Hub.

Register for Data Access

Tuskegee University has a Data Use and Registration Agreement (DURA) with the All of Us Research Program, allowing TU researchers access.

1. Sign up to use the Workbench (make an @researchallofus.org account)
2. Complete two-step verification with your @researchallofus.org account 
3. Verify identity with login.gov. For issues with this step, you can contact support@researchallofus.org (there can be issues even when info is input correctly). Alternative identity verification methods are available if you have a state ID, or phone number or SSN, US passport, or an e-passport. For alternative identity verification methods, contact support@researchallofus.org as well. 
4. Login to Researcher Workbench
5. Complete ethics training modules; TU users must complete relevant training in the Workbench profiles to access registered and controlled tiers data.
6. To check for access level, click the three-bar menu in the top upper left corner, click your name, and then click “Data Access Requirements."

Video Tutorials:

Onboarding Tutorial

https://www.youtube.com/watch?v=Y92Fa5L4SC0&list=PLR8euOCc1JWjJK_Dy8f5_ mWyOk-oH7pug

Introduction to Researcher Workbench

https://www.youtube.com/watch?v=NTLJtwLcavo&list=PLR8euOCc1JWjJK_Dy8f5_ mWyOk-oH7pug&index=4

WORKSPACES 

Registered researchers use workspaces to access, store, and analyze data for specific research projects. Workspaces are collaborative and can be shared among other registered researchers within a project team.

Video Tutorial:

https://support.researchallofus.org/hc/en-us/articles/6088655725716-How-to-Use-Workspace-Buckets-Using-R

https://support.researchallofus.org/hc/en-us/articles/6088642970004-How-to-Use-Workspace-Buckets-Using-Python

DATASET BUILDER 

The Dataset Builder allows researchers to search and save collections of health information about cohorts, called concept sets. Researchers can search and save concepts from a particular domain and use them in the Dataset Builder.

Video Tutorial:

https://www.youtube.com/watch?v=cUuDKUxjQoo&list=PLR8euOCc1JWhtKGGEnn

Br7l3Wgs5Zjx9W&index=6

Data Sets Include:

• Electronic Health Records (EHRs): Participants have the option to share EHR data, which is standardized using the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM).
• Biosamples and Bioassays: DNA is extracted via blood, urine, or saliva for subsequent genomic analysis.
• Mobile Health Data: Biometric data like heart rate and blood pressure are tracked using wearable devices.
• Physical Measurements: At the participant's first appointment, trained All of Us staff members measure and record information such as height, weight, BMI, waist and hip circumferences, blood pressure, heart rate, pregnancy status, and wheelchair use.
• Surveys: Participants in the All of Us Research Program respond to surveys spanning a variety of topics. The program has tested each survey for readability and accessibility using cognitive interviews and quantitative testing. This testing process included people from different educational backgrounds and geographic locations to capture a sample that reflects the U.S. population. After participants complete the core surveys (The Basics, Lifestyle, and Overall Health), they may complete additional surveys on other topics. For more information about the additional surveys and to explore their content, please visit the Survey Explorer.

NOTEBOOKS 

Researchers with R or Python experience can perform high-powered queries and analysis within the All of Us datasets using our integrated, cloud-based Jupyter Notebook environment.

Video Tutorial:

https://www.researchallofus.org/data-tools/workbench/

COHORT BUILDER 

The Cohort Builder is a custom, point-and-click tool that allows researchers to create, review, and annotate groups of participant data, or cohorts, within the All of Us dataset.

Video Tutorial:  

https://www.youtube.com/watch?v=G6_GG2CJ9mA&list=PLR8euOCc1JWhtKGGEnn Br7l3Wgs5Zjx9W&index=4

The All of Us Research Hub matches a broad research community with a diverse set of research participants. Its goal is to advance precision medicine research and fuel new insights into human health. The Research Hub houses one of the largest, most diverse, and most broadly accessible datasets ever assembled. It also provides an interactive Data Browser where anyone can learn about the type and quantity of data that All of Us collects. Users can explore aggregate data including genomic variants, survey responses, physical measurements, electronic health record information, and wearables data.

Registered users can use the Researcher Workbench to dive deeper into the data; conduct rapid, hypothesis-driven research; and build new methods for the future, using a variety of tools. The diverse data may help facilitate new studies that could help lead to new insights, treatments, and strategies for disease prevention that are tailored to individuals. Learn more about All of Us at AllofUs.nih.gov.

DATA BROWSER

The Data Browser provides interactive views of the publicly available All of Us Research Program aggregate-level participant data, including EHR domains, survey responses, and physical measurements.

DATA SNAPSHOTS

The Data Snapshots include data visualizations showing the participant cohort size and attributes, including how many participants are from groups underrepresented in biomedical research.

DATA ACCESS TIERS

The Research Hub’s data use policies and tiered-data access model support our commitment to data security and participant privacy.

• Data Access Tiers
  • Public Tier: The dataset contains only aggregate data with identifiers removed. These data are available to everyone through Data Snapshots and the Data Browser, an interactive tool on the Research Hub.
  • Registered Tier: The curated dataset contains deidentified individual-level data, available only to approved researchers on the Researcher Workbench. The Registered Tier currently includes data from electronic health records (EHRs), wearables, and surveys, as well as physical measurements taken during participant enrollment.
  • Controlled Tier: The dataset contains genomic data in the form of whole genome sequencing (WGS) and genotyping arrays, previously suppressed demographic data fields from EHRs and surveys, and unshifted dates of events.
• Data Methods
  • To ensure the Research Hub collects the highest quality data possible, the AoURP employs a comprehensive data methodology to curate data for registered researchers.

February 06, 2023

Contact: Thonnia Lee, Tuskegee University Office of Communications, Public Relations and Marketing
  

TUSKEGEE, Alabama -- Members of the extended Tuskegee community are invited to discuss the importance of engagement in research to better shape healthcare for residents of all ages. The All of Us Research Program, in partnership with Macon County community members, will host a Health Research Symposium at Bethel Missionary Baptist Church.  Community-centered gathering and conversations will be held from 6 p.m. to 8 p.m. on Thursday, Feb. 9 and the community-researcher partnership symposium is from 10 a.m. to 2:15 p.m. on Friday, Feb. 10.

During the symposium, there will be three panel discussion sessions focused on The Historical Context of Research: the need to heal and establish trust; From Yesterday to Today: Lessons learned from the past and practices in place, and Looking Toward Tomorrow: Opportunities to collaborate between researchers and the community. Dr. Karriem Watson, chief engagement officer of All of Us, and Dr. Stephen Olufemi Sodeke, resident bioethicist and professor of Bioethics at the Center for Biomedical Research at Tuskegee, will host the sessions. The panels, which will include other representatives from health and research fields, will address the history of research and clinical trials and identify areas that can improve collaborative opportunities between researchers and community members in Macon County.

“Stepping up to be counted because we count is burdensome and takes courage, but that is the kind of action that would ensure representation, and participation in the All of Us,” said Dr. Sodeke. “It supports efforts to increase the diversity of data critical to precision prevention, precision drug development, precision nutrition, and effective individualized treatments for equitable and better health outcomes for all of us.”

Special guests will include Lillie Head, president of the Voices of Our Fathers Legacy Foundation; Veronica Robinson of HELA100: The Henrietta Lacks Initiative; Christopher Williams with Quality of Life Health Services; Dr. Deneah Maxwell-Stafford of Rhema Health and Wellness; Dr. Clayton Yates, a Tuskegee professor of biology and director of the university’s multidisciplinary Center for Biomedical Research; Community Advocate Dr. Luceria Dunn and others.

The All of Us Research Program aims to collect, store securely, and study in a respectful manner, data and bio-specimens from 1 million or more, diverse individuals in the United States. Their mission is to accelerate health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us.

© 2023 Tuskegee University